Antipsychotics as the New Antidepressants

In case you were skeptical of the April 2 post. Here’s Furious Seasons (April 4 entry) with a quote from the maker of Seroquel describing it as an antidepressant.

A bizarre incident in Mississippi: a middle school student gave the antipsychotic Seroquel to several friends, the friends took the drug, the students began acting oddly, the students were taken to a hospital, and the student who gave them the drug is in big trouble.

Then this from a press account:

“Seroquel is an antidepressant drug used to treat manic depression, schizophrenia and bipolar disorder, according to the Web site”Where the hell does AstraZeneca get off describing the drug, which is not approved for depression, as an anti-depressant? The drug is approved for bipolar depression, but it’s most common use is as an antipsychotic, shut-people-up drug. If it’s an anti-depressant, then I am Zeus.

Kalea Chapman, Psy.D.


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Clinical Psychologist practicing in the Los Feliz neighborhood of Los Angeles, California.

3 thoughts on “Antipsychotics as the New Antidepressants”

  1. Hi Kalea. Nice web site. I’ve been prescribed a small dose (25 mg) of seroquel for agitated depression which I believe is now known as “mixed mania.” It works well for that.

    But as a patient, I would think that seroquel would be bad for just depression because in fact, although it mutes bad internal and external behavior, it also mutes good feelings. One of the side effects is that it makes me move around a little more slowly and see the world in a somber way. If I was just depressed, I think it would make me feel more depressed.


  2. Keep talking with your doctor, individual effects of these drugs vary enormously. If he or she is not listening, find a new doctor. Take care.


  3. i am bipolar and i am taking seroquel. i did not want to because it is an antiphycotic—stigma!!!!! i have had major depression for quite a while. i only take it because it helps me sleep. when i go awhile without taking it then sart taking it – it has helped with my mood alot!!!! after awhile though i do not see a difference– i still feel very depressed- almost suicidal. plus it can cause hyperlipidema, diabetes
    and cad–i have 2 of the side effects-all but diabetes,but probably had them bfore stating seoquel.


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